Search results for "Antioxidant statu"

Oxidative status in metabolic syndrome

2014

Impact of high-fat diet on antioxidant status, vascular wall thickening and cardiac function in adult female LDLR<sup>–/–</sup> mice

2012

International audience; Background: Western diet, rich in saturated fatty acids and cholesterol, is associated with increased cardiovascular risk. We thus investigated in female mice the influence of this diet on plasma antioxidant status, vascular wall thickening and cardiac function. Methods and Results: Adult female C57BL/6J wild type (WT) and LDLR–/– mice were fed a normal diet (ND) or a high-fat diet (HFD) for 17 weeks. HFD induced an increase in plasma lipids and vitamin C (Vit C) levels in both groups but at a much higher level in LDLR–/– and a decrease in plasma ascorbyl free radical levels to Vit C ratio (an endogenous oxidative stress index) in LDLR–/–. We only found a slight decr…

Oxidative status in nondiabetic middle-aged subjects with metabolic syndrome: preliminary data.

2013

In vitro effects of vitamins C and E, n-3 and n-6 PUFA and n-9 MUFA on placental cell function and redox status in type 1 diabetic pregnant women.

2016

IF 2.972; International audience; The aim of this investigation was to determine the in vitro effects of vitamin C and E, n-3 and n-6 PUFA and n-9 MUFA on placental cell proliferation and function in type 1 diabetes. Placenta tissues were collected from 30 control healthy and 30 type 1 diabetic women at delivery. Placental cells were isolated and were cultured in RPMI medium supplemented with vitamin C (50 μM), vitamin E (50 μM), n-3 PUFA (100 μM), n-6 PUFA (100 μM) or n-9 MUFA (100 μM). Cell proliferation, cell glucose uptake and intracellular oxidative status were investigated. Our results showed that basal placental cell proliferation, glucose uptake, malondialdehyde (MDA) and carbonyl p…

Behavior of the total antioxidant status in a group of subjects with metabolic syndrome.

2014

AIM: Our purpose was to examine the total antioxidant status (TAS) in subjects with metabolic syndrome (MS) subdivided according to the presence or not of diabetes mellitus. METHODS: We enrolled 106 subjects (45 women, 61 men) with MS subsequently subdivided in diabetics (14 women, 29 men) and nondiabetics (31 women, 29 men). TAS was obtained using an Assay kit which relies on the ability of plasma antioxidant substances to inhibit the oxidation of 2,2'-azino-bis(3-ethylbenzthiazoline sulfonic acid) to the radical ABTS+. RESULTS: In the group of MS subjects a significant decrease in TAS (p<0.05) in comparison with normal controls was evident. This difference was present between normal subje…

Relationship between elastase and total antioxidant status in young subjects with recent myocardial infarction

2008

In a group of young subjects with acute myocardial infarction (AMI) (68 men and 7 women; mean age 39.6 ± 5.7 years) we examined the plasma concentration of elastase, the thiobarbituric acid-reactive substances (TBARS) and the total antioxidant status (TAS) at the initial stage of AMI. In this group we found an increase of elastase (p <0.001) and TBARS (p < 0.001) and a decrease of TAS (p < 0.001). A statistical correlation was observed in the whole group of AMI patients between plasma elastase and TAS (p < 0.01) and this correlation was more statistically significant in patients with more risk factors and not in those with more involved vessels.

Uso di estratti antiossidanti di crusca di grano duro per ottenere una nuova pasta funzionale con l’approccio di arricchimento “da grano a grano”

2017

La crescente attenzione dei consumatori per gli alimenti funzionali ha stimolato le ricerche su nuovi tipi di pasta ottenuti con ingredienti in grado di migliorarne l’attività antiossidante, il profilo amminoacidico o il contenuto di acidi grassi polinsaturi e fibre, con risultati, però, non sempre soddisfacenti a causa di alterazioni delle proprietà tecnologiche e sensoriali della pasta (consistenza, tenuta alla cottura, odori e sapori inusuali). La crusca di grano duro contiene numerosi composti bioattivi, tra cui fenoli, carotenoidi e tococromanoli, che possono essere estratti con tecnologie green e reintegrati nell’impasto per ottenere prodotti con caratteristiche simili alla pasta trad…

Effects of extra-virgin olive oil enriched with E-vitamin and Q10-coenzyme on the heart rate variability and plasma antioxidant status in athletes

2010

OBJECTIVES: To examine whether the assumption of extra virgin olive oil enriched with E-vitamin and Q10-coenzyme may improve the plasma anti-oxidant/pro-oxidant balance and be associated with favorable changes in heart rate variability (HRV). METHODS: Four male athletes, mean age 22 (range 21-24), were recruited. They assumed 20 ml per day of the integrator (20 mg Q10 and 15 mg Vit E) for one month. The plasma antioxidant capacity (AC) was evaluated by the crocin bleaching assay. The frequency-domain analysis of HRV was carried out using Cardioline Cube recorder and specific software to obtain, from an autoregressive power spectrum approach, the power in normalized units (nu) of the low-(LF…

Défenses antioxydantes, inflammation et immunomodulation, au cours du diabète gestationnel, dans les compartiments maternel, foetal et placentaire

2010

Gestational diabetes mellitus (GDM) is defined as ‘carbohydrate intolerance of variable severity with onset or first recognition during pregnancy’, irrespective to necessary treatment and its evolution in the post partum. GDM is associated with a number of complications/ pathologies both in mother and in their newborns, with short and long-term. In this study, we investigated the role of cytokines, adipokines and antioxidant status during GDM and macrosomia. Our study has demonstrated that these pathologies are associated with a perturbation in lipid metabolism, and antioxidant and immune status. GDM is linked to the down-regulation of adiponectin along with Th1 cytokines and upregulation o…

Quality and antioxidant response of gilthead seabream (Sparus aurata L.) to dietary supplements of fenugreek (Trigonella foenum graecum) alone or com…

2017

The present study was conducted to determine the potential effect of the dietary intake of fenugreek (Trigonella foenum graecum) seeds alone or in combination with Bacillus licheniformis, Lactobacillus plantarum or B. subtilis on gilthead seabream quality and antioxidant response after 2 and 3 weeks of experimental feeding. The results showed that the supplements did not affect the percentage of the fatty acid profiles of muscle, demonstrating that all the additives tested can be administrated without any negative effect on biochemical composition and quality of gilthead seabream. The quantification of thiobarbituric acid reactive substances in muscle demonstrated the significant beneficial…